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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DYRK2
All Species:
19.7
Human Site:
S30
Identified Species:
30.95
UniProt:
Q92630
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92630
NP_003574.1
601
66652
S30
A
V
R
Q
L
Q
A
S
P
G
L
G
A
G
A
Chimpanzee
Pan troglodytes
XP_509205
601
66595
S30
L
V
R
A
C
T
A
S
P
G
L
G
A
G
A
Rhesus Macaque
Macaca mulatta
XP_001117134
601
66643
S30
A
V
R
Q
L
Q
A
S
P
G
L
G
A
G
A
Dog
Lupus familis
XP_538273
601
66656
S30
A
V
R
Q
L
Q
A
S
P
G
L
G
A
G
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4C9
599
66538
S30
A
V
R
Q
L
Q
A
S
P
G
I
G
A
G
A
Rat
Rattus norvegicus
Q4V8A3
586
65492
T34
L
G
D
G
V
Y
D
T
F
M
M
I
D
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511087
546
60615
Q36
G
Q
G
Q
I
Q
V
Q
Q
L
F
E
D
G
S
Chicken
Gallus gallus
Q5ZIU3
526
59419
V28
D
N
S
N
K
R
T
V
L
T
T
Q
P
N
G
Frog
Xenopus laevis
NP_001088793
567
63329
A31
Y
M
R
L
D
Q
M
A
A
Q
D
A
A
E
D
Zebra Danio
Brachydanio rerio
NP_001038298
587
65453
G33
S
P
G
L
G
I
G
G
P
R
A
G
A
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P83102
828
92722
T33
N
T
T
H
L
E
N
T
Q
L
S
K
A
L
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001023208
796
87422
Q62
L
Y
L
P
Q
I
P
Q
S
A
S
F
A
A
A
Sea Urchin
Strong. purpuratus
XP_799140
561
63192
T31
T
Q
G
D
T
A
T
T
A
L
Y
P
H
H
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51566
467
54180
Baker's Yeast
Sacchar. cerevisiae
P14680
807
91227
Q175
G
Y
Q
Q
Q
Q
Q
Q
V
Y
Q
Q
G
A
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
99.6
98.3
N.A.
97
59.7
N.A.
78.6
81.3
64.5
83.6
N.A.
43.3
N.A.
45.7
63.7
Protein Similarity:
100
98.8
99.8
99
N.A.
98.5
71.8
N.A.
83
84.5
75
89.8
N.A.
54.9
N.A.
55.6
73.5
P-Site Identity:
100
73.3
100
100
N.A.
93.3
0
N.A.
20
0
20
26.6
N.A.
13.3
N.A.
13.3
0
P-Site Similarity:
100
73.3
100
100
N.A.
100
20
N.A.
33.3
6.6
33.3
33.3
N.A.
33.3
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.3
27.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.6
41.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
27
0
0
7
0
7
34
7
14
7
7
7
60
14
40
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
7
7
0
7
0
0
0
7
0
14
0
7
% D
% Glu:
0
0
0
0
0
7
0
0
0
0
0
7
0
14
0
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
7
7
0
0
0
% F
% Gly:
14
7
20
7
7
0
7
7
0
34
0
40
7
47
14
% G
% His:
0
0
0
7
0
0
0
0
0
0
0
0
7
7
0
% H
% Ile:
0
0
0
0
7
14
0
0
0
0
7
7
0
0
7
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
0
7
0
0
0
% K
% Leu:
20
0
7
14
34
0
0
0
7
20
27
0
0
7
0
% L
% Met:
0
7
0
0
0
0
7
0
0
7
7
0
0
0
0
% M
% Asn:
7
7
0
7
0
0
7
0
0
0
0
0
0
7
0
% N
% Pro:
0
7
0
7
0
0
7
0
40
0
0
7
7
0
0
% P
% Gln:
0
14
7
40
14
47
7
20
14
7
7
14
0
0
0
% Q
% Arg:
0
0
40
0
0
7
0
0
0
7
0
0
0
0
0
% R
% Ser:
7
0
7
0
0
0
0
34
7
0
14
0
0
0
14
% S
% Thr:
7
7
7
0
7
7
14
20
0
7
7
0
0
0
14
% T
% Val:
0
34
0
0
7
0
7
7
7
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
14
0
0
0
7
0
0
0
7
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _